TIME-SAVING METHOD FOR DIRECTLY AMPLIFYING AND CAPTURING A MINIMAL AMOUNT OF PANCREATIC TUMOR-DERIVED MUTATIONS FROM FINE-NEEDLE ASPIRATES USING DIGITAL PCR

Abstract It is challenging to secure a cytopathologic diagnosis using minute amounts of tumor fluids and tissue fragments.Hence, we developed a rapid, accurate, low-cost method for detecting tumor cell-derived DNA from T-Shirts limited amounts of specimens and samples with a low tumor cellularity, to detect KRAS mutations in pancreatic ductal carci

Traits such as clutch size vary markedly across species and environmental gradients but have usually been investigated from either a comparative or a geographic perspective, respectively.We analyzed the global variation in clutch size across 5,290 bird species, excluding brood parasites and pelagic species.We integrated intrinsic (morphological, be

The superconducting state of the heavy-fermion metal UTe_{2} has attracted considerable interest because of evidence of spin-triplet Cooper pairing and nontrivial topology.Progress on these questions requires identifying the presence or absence of nodes in the superconducting gap function and their dimension.In this article, we report a comprehensi

The belief that talented people create prosperous organizations contributed to the accomplishment of talent management concepts into reality.Highly capable professionals or talented employees who systematically nurtured the best skills typically demonstrate high performance and serve as one of the key success factors for the organizations.Organizat